Title of article
Ligand acceleration in ZnI2-catalyzed intramolecular hydroamination of unfunctionalized olefins
Author/Authors
Liu، نويسنده , , Gong-Qing and Li، نويسنده , , Wei and Wang، نويسنده , , Yu-Mei and Ding، نويسنده , , Zhen-Ying and Li، نويسنده , , Yue-Ming، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
4393
To page
4396
Abstract
Zinc halide-promoted hydroamination of 4-penten-1-amine compounds was studied. Preliminary results indicated that both steric and electronic factors are crucial for this Lewis acid-promoted reaction. ZnI2 gave the most promising results and the reactivity could be further increased upon addition of a suitable ligand. Up to 95% isolated yields were obtained when the reactions were carried out in 1,4-dioxane in the presence of 10 mol % of ZnI2 and 8-hydroxyquinoline.
Keywords
Ligand acceleration , Zinc iodide , Hydroamination , Unfunctionalized olefins , 4-Penten-1-amine
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881541
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