Title of article
A scalable approach to diaminopyrazoles using flow chemistry
Author/Authors
Wilson، نويسنده , , Noel S. and Osuma، نويسنده , , Augustine T. and Camp، نويسنده , , Jennifer A.Van and Xu، نويسنده , , Xiangdong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
4498
To page
4501
Abstract
This Letter reports on how the combination of microwave and continuous flow chemistry facilitated the convenient preparation of aminopyrazoles from commercial aryl halides. The method was applied to a variety of substrates with good to excellent yields and further extended toward the complete flow synthesis of 5,7-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-2-amine.
Keywords
Sequential flow process , Aminopyrazole , Pyrazolopyrimidine , Flow chemistry , Single mode microwave
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881581
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