Title of article
Rapid synthesis of methoxyconidiol and conitriol stereoisomers
Author/Authors
Lopez، نويسنده , , Gérald and Witczak، نويسنده , , Anne and Menniti، نويسنده , , Christophe and Inguimbert، نويسنده , , Nicolas and Banaigs، نويسنده , , Bernard، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
4548
To page
4550
Abstract
We describe the diastereoselective synthesis of the marine meroterpenes methoxyconidiol and conitriol in their trans form from the readily available 1-bromo-2,5-dimethoxybenzene in only three steps. The choice of the protective group strategy influenced not only the overall reaction yields but also the diastereoisomeric ratio. In addition, we describe the synthesis of natural conitriol (cis form) for the first time.
Keywords
Conitriol , diastereoselective synthesis , Methoxyconidiol , Meroterpenes
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881603
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