Author/Authors :
Mino، نويسنده , , Takashi and Hashimoto، نويسنده , , Masatoshi and Uehara، نويسنده , , Katsunori and Naruse، نويسنده , , Yoshiaki and Kobayashi، نويسنده , , Shohei and Sakamoto، نويسنده , , Masami and Fujita، نويسنده , , Tsutomu، نويسنده ,
Abstract :
Chiral dihydrobenzofuran-based diphosphine ligand (BICMAP) 1 was used as a ligand for the rhodium(I)-catalyzed asymmetric 1,4-addition of arylboronic acids to cyclic enones up to 99% ee. We also found that the BICMAP-rhodium system was an efficient catalyst for the 1,4-addition of alkenylboronic acids to 2-cyclohexenone in good enantioselectivities.
Keywords :
Asymmetric reaction , 1 , 4-addition , Rhodium catalyst , Diphosphine
