Title of article :
Highly enantioselective hydrogenation of new 2-functionalized quinoline derivatives
Author/Authors :
Maj، نويسنده , , Anna M. and Suisse، نويسنده , , Isabelle and Méliet، نويسنده , , Catherine and Hardouin، نويسنده , , Christophe and Agbossou-Niedercorn، نويسنده , , Francine، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
The asymmetric hydrogenation of a new series of 2-functionalized quinolines has been developed in the presence of in situ generated catalysts obtained from [Ir(cod)Cl]2/(R)-bisphosphine/I2 combinations. The enantioselectivity levels were as high as 84–94% ee for the synthesis of 1,2,3,4-tetrahydroquinolines.
Keywords :
Asymmetric catalysis , iridium , Quinolines , Hydrogenation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
