Title of article
Biomimetic synthesis of Cbz-(S)-dolaphenine
Author/Authors
Garcيa-Reynaga، نويسنده , , Pablo and VanNieuwenhze، نويسنده , , Michael S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
5
From page
4989
To page
4993
Abstract
A new route to Cbz-(S)-dolaphenine, a recurring element in bioactive peptidic natural products, has been implemented, which closely parallels the biogenetic pathway. Cyclodehydration of 11 to yield thiazoline 2 allows for a Ni(0)-promoted decarbonylative aromatization to provide the thiazole framework with retention of stereochemistry.
Keywords
Decarbonylation , biomimetic , Thiazoline , cyclodehydration , Thiazole
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881906
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