Title of article
Preparation of enol ester epoxides and their ring-opening to α-silyloxyaldehydes
Author/Authors
Gregory K. Friestad، نويسنده , , Gregory K. and Sreenilayam، نويسنده , , Gopeekrishnan and Cannistra، نويسنده , , Joseph C. and Slominski، نويسنده , , Luke M.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
5064
To page
5067
Abstract
The Z-selective ruthenium-catalyzed addition of aromatic carboxylic acids to alkynes was followed by dioxirane epoxidation to furnish enol ester epoxides with cis configuration. Upon treatment of enol ester epoxides with tert-butyldimethylsilyl triflate in the presence of 2,6-lutidine, synthetically useful α-silyloxyaldehydes were obtained. This novel transformation was facilitated by microwave irradiation.
Keywords
Enol esters , epoxides , Oxidation , Aldehydes
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881945
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