Author/Authors :
Gallo، نويسنده , , Rafael D.C. and Ferreira، نويسنده , , Irlon M. and Casagrande، نويسنده , , Gleison A. and Pizzuti، نويسنده , , Lucas and Oliveira-Silva، نويسنده , , Diogo and Raminelli، نويسنده , , Cristiano، نويسنده ,
Abstract :
The reaction of aromatic and heteroaromatic compounds with molecular iodine in the presence of aqueous hydrogen peroxide using water without any co-solvent at 50 °C for 24 h produced versatile iodinated organic molecules with potential application in organic synthesis and medicine in very good yields. In addition, a mechanistic investigation for the iodination process was carried out by mass spectrometry.
Keywords :
Mechanistic investigation , mass spectrometry , Iodination reaction , Iodinated compounds , Water as solvent