Title of article
Microwave-assisted Claisen rearrangement of naphthyl 2-propynyl ethers: synthesis of naphthofurans
Author/Authors
Prasada Rao Lingam، نويسنده , , V.S. and Dahale، نويسنده , , Dnyaneshwar H. and Mukkanti، نويسنده , , Kagga and Gopalan، نويسنده , , Balasubramanian and Thomas، نويسنده , , Abraham، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
5695
To page
5698
Abstract
An efficient two-step approach for the synthesis of naphtho[1,2-b]furans and naphtho[2,1-b]furans has been developed. Various functionalized propargyl alcohols were etherified with α- or β-naphthol under Mitsunobu reaction conditions to give naphthyl 2-propynyl ethers, which underwent a facile microwave-assisted Claisen rearrangement and concomitant anionic cyclization to yield naphthofuran derivatives under basic reaction conditions.
Keywords
Claisen rearrangement , Mitsunobu reaction , Cesium fluoride , 2-b]furans , Naphthyl 2-propynyl ethers , 1-b]furans , microwave irradiation
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1882354
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