Title of article :
A novel strategy for the chiral 2,4,5-triol moiety and its application to the synthesis of seimatopolide A and (2S,3R,5S)-(−)-2,3-dihydroxytetradecan-5-olide
Author/Authors :
Reddy، نويسنده , , B. Phaneendra and Pandurangam، نويسنده , , Arland T. and Yadav، نويسنده , , J.S. and Reddy، نويسنده , , B.V. Subba، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
A highly stereoselective approach to the total synthesis of seimatopolide A and (2S,3R,5S)-(−)-2,3-dihydroxytetradecan-5-olide is described via a common polyketide precursor by means of Prins reaction and MacMillan aminoxylation sequence.
Keywords :
McMillan aminoxylation , 2 , Prins cyclization , 4 , 5-Triols , Ring closing metathesis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
