Title of article :
Enzymatic synthesis of N-acylethanolamines: direct method for the aminolysis of esters
Author/Authors :
Whitten، نويسنده , , Kyle M. and Makriyannis، نويسنده , , Alexandros and Vadivel، نويسنده , , Subramanian K.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
Immobilized Candida antarctica (Novozyme 435) catalyzed synthesis of N-acylethanolamines is described. Treatment of methyl esters with lipase and amines yielded the desired amides within 2–24 h with yields ranging from 41% to 98%.
Keywords :
Biocatalysis , Amidation , Candida antarctica , Endogenous ligand , N-Acylethanolamines
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
