Title of article :
Synthesis and application of proline based organocatalyst for highly enantioselective aldol reaction by hydrogen bonding
Author/Authors :
Thorat، نويسنده , , Prashant B. and Goswami، نويسنده , , Santosh V. and Khade، نويسنده , , Bhimrao C. and Bhusare، نويسنده , , Sudhakar R.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
Using hydrogen bond based concept we have synthesized new organocatalysts and have applied them to catalyze direct asymmetric aldol reaction. Reaction proceeded efficiently and gave high yield with excellent diastereoselectivity and enantioselectivity.
Keywords :
aldol reaction , diastereoselectivity , Enantioselectivity , organocatalysis , Hydrogen bonding
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
