Title of article :
Cerium metal- mediated Reformatsky-type reaction with ethyl bromosuccinate for the synthesis of novel paraconic acid analogs
Author/Authors :
Rodrigues، نويسنده , , Shirley M.M. and Nardini، نويسنده , , Viviani and Constantino، نويسنده , , Mauricio G. and da Silva، نويسنده , , Gil Valdo J.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
The treatment of cerium metal with ethyl bromosuccinate (1) forms the stabilized organolanthanoid intermediate (2), which reacts with carbonyl compounds in a Reformatsky-type reaction, under mild conditions, to produce functionalized γ-substituted paraconic acids (4) in good yields.
Keywords :
Ethyl bromosuccinate , Cerium metal , Reformatsky-type reaction , Paraconic acids
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
