Title of article
Calcium catalyzed hydroalkoxylation
Author/Authors
Kena Diba، نويسنده , , Anastasie and Begouin، نويسنده , , Jeanne-Marie and Niggemann، نويسنده , , Meike، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
6629
To page
6632
Abstract
A calcium catalyzed intramolecular hydroalkoxylation reaction is presented, as a transition metal free, inexpensive, and very mild process for the highly atom economic formation of cyclic ethers from γ,δ-unsaturated alcohols. In contrast to most of the previously reported procedures, room temperature conditions are fully sufficient in most cases for a high yielding cycloisomerization in the presence of a combination of 5 mol-% Ca(NTf2)2 and 5 mol-% Bu4NPF6. Full regioselectivity is observed in all transformations.
Keywords
Lewis acid , Calcium , Hydroalkoxylation , Oxygen heterocycles , cyclization
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1882846
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