Title of article
A facile one-pot synthesis of 2-thioxo-dihydropyrimidines and polyfunctionalized pyran derivatives as mimics of novel calcium channel modulators
Author/Authors
S. K. Yadlapalli، نويسنده , , Rama Krishna and Chourasia، نويسنده , , O.P. and Perali، نويسنده , , Ramu Sridhar، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
6725
To page
6728
Abstract
An efficient protocol for the synthesis of pharmacologically significant dihydropyrimidines and polyfunctionalized pyrans is described by performing a one-pot multicomponent reaction (MCR). A chemistry-driven drug discovery approach is implemented by keeping an essential skeleton of calcium channel modulators in all the synthesized derivatives.
Keywords
Dihydropyrimidines , Polyfunctionalized pyrans , Calcium channel modulator , Multi-component reaction , Piperidinylamide
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1882888
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