Title of article
A facile sequential three-component regio- and stereoselective synthesis of novel spiro-isoxazoline/acridinone hybrids
Author/Authors
Uma Maheswari، نويسنده , , Shanmugavel and Perumal، نويسنده , , Subbu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
6885
To page
6888
Abstract
A series of novel spiro-isoxazoline/acridinone hybrids has been synthesized regio- and stereoselectively via three-component sequential reactions of 3,4-dihydroacridin-1(2H)-one, aromatic aldehydes and benzohydroximinoyl chlorides in the presence of potassium hydroxide at ambient temperature in good yields. This one pot three-component sequential transformation proceeds via Knoevenagel condensation/1,3-dipole generation/1,3-dipolar cycloaddition sequence.
Keywords
Spiroisoxazolyl–acridinones , Nitrile oxides , 1 , 3-dipolar cycloaddition , 4-Dihydroacridin-1(2H)-one , 3
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1883013
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