Author/Authors :
Manzo، نويسنده , , Emiliano and Pagano، نويسنده , , Dario and Nuzzo، نويسنده , , Genoveffa and Gavagnin، نويسنده , , Margherita and Ciavatta، نويسنده , , Maria Letizia، نويسنده ,
Abstract :
Parazoanthine A (7.0% overall yield) and its O-methyl derivative (6.2% overall yield) were prepared by a concise biomimetic synthesis based on the coupling reaction of l-arginine methyl ester dihydrochloride with isocyanate derivatives of p-coumaric acid and 4-methoxy-cinnamic acid, respectively. The synthetic approach is designed to obtain a wider class of parazoanthine analogs.
