Title of article
Synthesis of unit-B of cryptophycin-24 via Sharpless asymmetric dihydroxylation
Author/Authors
Borah، نويسنده , , Arun Jyoti and Goswami، نويسنده , , Progyashree and Barua، نويسنده , , Nabin C. and Phukan، نويسنده , , Prodeep، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
7128
To page
7130
Abstract
A synthetic pathway for the synthesis of unit-B of cryptophycin-24 has been developed using Sharpless asymmetric dihydroxylation as the key step. This study shows that direct azidation of α-hydroxy acid ester using diphenylphosphoryl azide is beneficial to asymmetric synthesis of α-amino acid without the loss of chirality during the transformation.
Keywords
Hydrogenolysis , sharpless asymmetric dihydroxylation , ?-Amino acid , Diphenylphosphoryl azide , Cryptophycin
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1883186
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