Author/Authors :
Altava، نويسنده , , Belén and Isabel Burguete، نويسنده , , M. and Carbَ، نويسنده , , Noèlia and Luis، نويسنده , , Santiago V. and Martي-Centelles، نويسنده , , Vicente and Vicent، نويسنده , , Cristian، نويسنده ,
Abstract :
A family of bis(amino amides) derived from natural amino acids has been synthesized and tested for the NMR enantiodiscrimination, as chiral receptors, of some N-protected dicarboxylic amino acids. The influence of the amino acid side chain is an important parameter to obtain good enantiodiscrimination. The binding between bis(amino amides) and N-protected dicarboxylic amino acids has been thoroughly studied by ESI-MS and NMR spectroscopic methods as well as by molecular modeling.
Keywords :
Bis(amino amides) , chiral receptors , CSA , Dicarboxylic amino acids , Enantiodiscrimination
