PhI(OAc)2-mediated oxidative trifluoromethylation of arenes with CF3SiMe3 under metal-free conditions

A PhI(OAc)2-mediated oxidative trifluoromethylation of arenes with CF3SiMe3 under metal-free conditions has been described. This protocol precludes the need of substrate pre-functionalization and metal catalysts, enabling a direct access to a series of trifluoromethylated arenes and heterocycles containing common functional groups in moderate and good yields.