Title of article :
Efficient synthesis of chlorohydrins using ClCH2MgCl·LiCl
Author/Authors :
Nishimura، نويسنده , , Rodolfo H.V. and Toledo، نويسنده , , Fabiano T. and Lopes، نويسنده , , Joمo L.C. and Clososki، نويسنده , , Giuliano C.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
The mixed lithium–magnesium carbenoid ClCH2MgCl·LiCl was easily generated in THF through the reaction of chloroiodomethane with i-PrMgCl·LiCl at −78 °C. This reagent reacts well with a number of aldehydes to give the corresponding chlorohydrins in good yields.
Keywords :
carbenoids , Chlorohydrins , organomagnesium , Turbo Grignard , lithium chloride
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
