Author/Authors :
Chinta Rao، نويسنده , , T.S. and Saha، نويسنده , , Sanjay and Raolji، نويسنده , , Gajendra B. and Patro، نويسنده , , Balaram and Risbood، نويسنده , , Prabhaker and Difilippantonio، نويسنده , , Michael J. and Tomaszewski، نويسنده , , Joseph E. and Malhotra، نويسنده , , Sanjay V.، نويسنده ,
Abstract :
A concise synthesis of a potent lead in anticancer therapeutics, sempervirine, was achieved by one pot Westphal condensation, ester hydrolysis, and decarboxylation under microwave irradiation. The method was extended to the synthesis of several similar heterocycles.
Keywords :
Westphal condensation , Microwave assisted , DNA intercalator , Sempervirine , Antiproliferative agent
