Author/Authors :
Nogoshi، نويسنده , , Keisuke and Domon، نويسنده , , Daisuke and Fujiwara، نويسنده , , Kenshu and Kawamura، نويسنده , , Natsumi and Katoono، نويسنده , , Ryo and Kawai، نويسنده , , Hidetoshi and Suzuki، نويسنده , , Takanori، نويسنده ,
Abstract :
The EF-ring of ciguatoxin 3C, a marine toxin from the dinoflagellate Gambierdiscus toxicus, was stereoselectively synthesized by iterative use of a cyclic ether formation process based on chirality-transferring Ireland-Claisen rearrangement and ring-closing olefin metathesis.
Keywords :
natural product synthesis , Ireland-Claisen rearrangement , stereoselective synthesis , Fused cyclic ethers , Ring closing olefin metathesis
