Author/Authors :
Venkata Rao، نويسنده , , K. and Balakumar، نويسنده , , C. and Lakshmi Narayana، نويسنده , , B. and Pran Kishore، نويسنده , , D. and Rajwinder، نويسنده , , K. and Raghuram Rao، نويسنده , , A.، نويسنده ,
Abstract :
A facile one-pot method is reported for the synthesis of 4-alkoxy-2-aminothiophene-3-carbonitriles. Transesterification of trimethylorthoacetate technique allowed introducing alkoxy substituents into 2-aminothiophene ring system. Diverse alkoxy substituents could be introduced efficiently by using this methodology. Further the synthesis of some of new 4-alkylamino-2-aminothiophenes is also reported.
Keywords :
2-Aminothiophenes , Transesterification , Gewald reaction , 4-Alkoxythiophenes
