Title of article
An efficient synthesis of pyrido-imidazodiazepinediones
Author/Authors
Arama، نويسنده , , Dominique P. and Lisowski، نويسنده , , Vincent and Scarlata، نويسنده , , Eliana and Fulcrand، نويسنده , , Pierre and Maillard-Boyer، نويسنده , , Ludovic T. and Martinez، نويسنده , , Jean and Masurier، نويسنده , , Nicolas، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
1364
To page
1367
Abstract
We herein report the synthesis of a series of 12 optically pure 3,4-dihydro-1H-pyrido-[1′,2′:1,2]-imidazo[4,5-d][1,3]diazepine-2,5-diones, which form a new family of azaheterocycle-fused [1,3]diazepines. The key step of the synthesis consists in a selective C-acylation of 2-amino-imidazo[1,2-a]pyridine by various natural amino-acids, followed by an intracarbonylation reaction.
Keywords
Diazepinones , Friedel–Crafts acylation , 2-a]pyridine , Polyfused heterocycles , Urea derivatives
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1883928
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