Title of article :
Cu-mediated selective O-arylation on C-6 substituted pyridin-2-ones
Author/Authors :
Chen، نويسنده , , Taijie and Huang، نويسنده , , Qingqing and Luo، نويسنده , , Yu and Hu، نويسنده , , Youhong and Lu، نويسنده , , Wei، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A practical and mild strategy has been developed for the selective O-arylation on C-6 substituted pyridin-2-ones with a series of arylboronic acids, using Cu(OTf)2 as the catalyst, DABCO as the ligand, Et3N as the base, and K2HPO4 as the additive. This method affords O-arylated pyridin-2-ones with good selectivity and yields
Keywords :
Chan–Evans–Lam cross-coupling , Arylboronic acids , O-Arylation , Selectivity , Pyridin-2-ones
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
