Author/Authors :
Yan، نويسنده , , Pu-Cha and Zhang، نويسنده , , Xian-Yi and Hu، نويسنده , , Xiaowei and Zhang، نويسنده , , Bin and Zhang، نويسنده , , Xiang-Dong and Zhao، نويسنده , , Michael and Che، نويسنده , , Daqing and Li، نويسنده , , Yuan-Qiang and Zhou، نويسنده , , Qi-Lin، نويسنده ,
Abstract :
An asymmetric synthesis of Silodosin was accomplished in high yield via catalytic hydrogenation of α,β-unsaturated carboxylic acid derivatives by using chiral catalyst Ir-SIPHOX, followed by Curtius rearrangement.
Keywords :
silodosin , asymmetric hydrogenation , Ir-SIPHOX catalyst , ? , ?-Unsaturated carboxylic acid
