Total synthesis of (±)-mimosifoliol by lateral lithiation
Author/Authors :
Slabu، نويسنده , , Iustina and Rossington، نويسنده , , Steven B. and Killoran، نويسنده , , Patrick M. and Hirst، نويسنده , , Nicholas I. Wilkinson، نويسنده , , James A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Pages :
2
From page :
1489
To page :
1490
Abstract :
A two-step protocol has been developed to allow the vinylation of diarylmethanes at the bridging CH2 using lateral lithiation and formylation followed by a Wittig reaction. This methodology has been applied in the racemic synthesis of the natural product mimosifoliol.
Keywords :
Organolithium chemistry , natural products , total synthesis
