Author/Authors :
Cheng، نويسنده , , Xiang-Rong and Ren، نويسنده , , Jie and Wang، نويسنده , , Chun-Hui and Guan، نويسنده , , Bin and Qin، نويسنده , , Jiang-Jiang and Yan، نويسنده , , Shi-Kai and Jin، نويسنده , , Hui-Zi and Zhang، نويسنده , , Wei-Dong، نويسنده ,
Abstract :
Four unprecedented C17-pseudoguaianolides with extended side chains, hookerolides A–D (1–4), were isolated from the whole plants of Inula hookeri. Their structures and absolute configurations were elucidated by a combination of NMR spectroscopy, CD spectrum, and the modified Mosher method. The in vitro bioactivity evaluation suggested that 1–4 possessed moderate to weak anti-inflammatory and cytotoxic properties.
Keywords :
Inula hookeri , Pseudoguaianolide , cytotoxicity , Anti-inflammation
