Title of article
Hookerolides A–D, the first naturally occurring C17-pseudoguaianolides from Inula hookeri
Author/Authors
Cheng، نويسنده , , Xiang-Rong and Ren، نويسنده , , Jie and Wang، نويسنده , , Chun-Hui and Guan، نويسنده , , Bin and Qin، نويسنده , , Jiang-Jiang and Yan، نويسنده , , Shi-Kai and Jin، نويسنده , , Hui-Zi and Zhang، نويسنده , , Wei-Dong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
1943
To page
1946
Abstract
Four unprecedented C17-pseudoguaianolides with extended side chains, hookerolides A–D (1–4), were isolated from the whole plants of Inula hookeri. Their structures and absolute configurations were elucidated by a combination of NMR spectroscopy, CD spectrum, and the modified Mosher method. The in vitro bioactivity evaluation suggested that 1–4 possessed moderate to weak anti-inflammatory and cytotoxic properties.
Keywords
Inula hookeri , Pseudoguaianolide , cytotoxicity , Anti-inflammation
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884164
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