Cu-catalyzed decarboxylative coupling of propiolic acids with boronic acids

A mild procedure of Cu-catalyzed decarboxylative cross-coupling of aryl- and alkynyl-boronic acids for construction of unsymmetrical substituted alkynes has been developed. The usage of inexpensive copper chloride as catalyst, and employing stable alkynl carboxylic acids and boronic acids as the substrates under oxidative conditions for sp–sp2 coupling, make this method very easy to operate.