• Title of article

    Expeditious synthesis of chiral 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazines

  • Author/Authors

    Bhowmik، نويسنده , , Subhendu and Kumar، نويسنده , , Anil K.S. and Batra، نويسنده , , Sanjay، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2013
  • Pages
    4
  • From page
    2251
  • To page
    2254
  • Abstract
    An expeditious one-pot two-step synthesis of chiral 4-substituted-6-methyl-1,2-dihydropyrrolo[1,2-a]pyrazin-3(4H)-ones via reaction between 5-methyl furfurylamine and N-Boc amino acids is described. LiAlH4-mediated reduction of 4-substituted-6-methyl-1,2-dihydropyrrolo[1,2-a]pyrazin-3(4H)-ones affords respective chiral 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazines in excellent yields.
  • Keywords
    1 , 2 , 3 , Amino acid , 2-a]pyrazines , Reduction , Furfurylamine , Chiral
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2013
  • Journal title
    Tetrahedron Letters
  • Record number

    1884303