Title of article :
Asymmetric organocatalytic Michael–hemiacetalization reaction: access to chiral spiro cis-δ-lactones by in situ oxidation of spiro δ-lactols
Author/Authors :
Wei، نويسنده , , Mo-Hui and Zhou، نويسنده , , Yi-Rong and Gu، نويسنده , , Liang-Hu and Luo، نويسنده , , Fan and Zhang، نويسنده , , Fang-Lin، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
Asymmetric tandem Michael–hemiacetalization reaction between 1-nitromethylcycloalkanol and α,β-unsaturated aldehydes was investigated, which provided an efficient and facile synthesis for spiro cis-δ-lactones by in situ oxidation of spiro δ-lactols in good overall yields with high to excellent enantioselectivities and diastereoselectivities.
Keywords :
organocatalysis , Asymmetric catalysis , Cascade reaction , Spirolactone
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
