Author/Authors :
Hong، نويسنده , , Keum-Hee and Lim، نويسنده , , Soo-Yeon and Yun، نويسنده , , Mi-Yeon and Lim، نويسنده , , Joo-Won and Woo، نويسنده , , Je-Hyuk and Kwon، نويسنده , , Hyockman and Kim، نويسنده , , Hae-Jo، نويسنده ,
Abstract :
A bromoacetyl functionalized fluorescein chemodosimeter (1) was utilized as a fluorescent probe for cysteine. The probe showed a selective and sensitive response to cysteine over homocysteine and glutathione in aqueous buffer through a rapid cyclization reaction. When cysteine was added, a fast fluorescence turn-on change of 1 was observed, thus allowing cysteine to be discriminated from other biothiols and micromolar concentrations of cysteine to be detected by the naked eye.
Keywords :
Chemodosimeter , Cysteine , probe , fluorescence
