Title of article :
Enantioselective fluorination of α-chloro-β-keto phosphonates in the presence of chiral palladium complexes
Author/Authors :
Woo، نويسنده , , Saet Byeol and Suh، نويسنده , , Chang Won and Koh، نويسنده , , Kwang Oh and Kim، نويسنده , , Dae Young، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
The catalytic enantioselective electrophilic fluorination of α-chloro-β-keto phosphonates promoted by chiral palladium complexes has been developed, allowing facile synthesis of the corresponding α-chloro-α-fluoro-β-keto phosphonates with excellent enantioselectivity (up to 95% ee).
Keywords :
?-Chloro-?-keto phosphonates , Chiral palladium catalysts , Asymmetric catalysis , Electrophilic fluorination
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
