Title of article :
Facile and scalable preparation of 2-imidazolylpyridines
Author/Authors :
Raba، نويسنده , , Andreas and Anneser، نويسنده , , Markus R. and Jantke، نويسنده , , Dominik and Cokoja، نويسنده , , Mirza and Herrmann، نويسنده , , Wolfgang A. and Kühn، نويسنده , , Fritz E.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A novel method for the synthesis of 2-imidazolylpyridines is presented. The reaction of 2-halopyridines, potassium carbonate, and imidazole at high temperatures under inert gas atmosphere leads exclusively to the formation of 2-imidazolylpyridines in high yields. The synthesis is scalable, comparatively inexpensive, and the products are easily isolable.
Keywords :
nucleophilic aromatic substitution , Solvent free synthesis , 2-Imidazolylpyridine , Metal free coupling
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
