Title of article :
Enantioselective decarboxylative aldol addition of β-ketoacids to isatins catalyzed by binaphthyl-modified organocatalyst
Author/Authors :
Suh ، نويسنده , , Chang Won and Chang، نويسنده , , Chul Woo and Choi، نويسنده , , Keon Woong and Lim، نويسنده , , Young Jo and Kim، نويسنده , , Dae Young، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
The catalytic enantioselective decarboxylative aldol addition reaction of isatins with β-ketoacids promoted by chiral bifunctional organocatalysts have been developed, allowing facile synthesis of the corresponding chiral 3-hydroxy-3-phenacyloxindole derivatives with excellent enantioselectivity (up to 97% ee).
Keywords :
Isatins , ?-ketoacids , 3-Hydroxy oxindole , Aldol addition , organocatalysis , Asymmetric catalysis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
