Title of article :
Nagelamides U–W, bromopyrrole alkaloids from a marine sponge Agelas sp.
Author/Authors :
Tanaka، نويسنده , , Naonobu and Kusama، نويسنده , , Taishi and Takahashi-Nakaguchi، نويسنده , , Azusa and Gonoi، نويسنده , , Tohru and Fromont، نويسنده , , Jane and Kobayashi، نويسنده , , Jun’ichi، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
Three new structurally unique bromopyrrole alkaloids, nagelamides U–W (1–3), were isolated from a marine sponge Agelas sp. Nagelamides U (1) and V (2) possess a γ-lactam ring with an N-ethanesulfonic acid and guanidino moieties, while nagelamide W (3) has two aminoimidazole moieties in the molecule. The structures of 1–3 were elucidated on the basis of spectroscopic data. Nagelamides U (1) and W (3) exhibited antimicrobial activity against Candida albicans.
Keywords :
Bromopyrrole alkaloids , Agelas sp. , Nagelamides U–W , Marine sponge
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
