Title of article
Synthesis of 1,8-dioxooctahydroxanthene C-nucleosides
Author/Authors
Manna، نويسنده , , Chinmoy and Samanta، نويسنده , , Sintu Kumar and Ghosh، نويسنده , , Sudip Kumar and Pathak، نويسنده , , Tanmaya، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
3971
To page
3973
Abstract
Since reactions between carbohydrates and cyclic 1,3-dicarbonyl compounds do not produce 1,8-dioxooctahydroxanthenes in general, reaction strategies have been devised to generate new 1,8-dioxooctahydroxanthene C-nucleosides by reacting sugars masked with acid-labile protecting groups and with free hydroxyl groups with 1,3-cyclohexanedione or dimedone. Some of these compounds are more cytotoxic to the cancer cells than against normal fibroblasts.
Keywords
1 , Cyclic sugar aldehyde , 3-dicarbonyls , cytotoxicity , Knoevenagel reaction , 8-Dioxooctahydroxanthene C-nucleosides , 1
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885028
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