Title of article
aza-Annulation of β-aminovinyl trifluoromethyl ketones with acryloyl chloride: an efficient synthesis of 5-(trifluoroacetyl)-3,4-dihydro-2(1H)-pyridinones
Author/Authors
Lyutenko، نويسنده , , Nataliya V. and Gerus، نويسنده , , Igor I.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
4091
To page
4093
Abstract
The first example of aza-annulation of β-aminovinyl trifluoromethyl ketones with acryloyl chloride has been studied. 5-Trifluoroacetyl-containing 3,4-dihydro-2(1H)-pyridinones 3a–j were obtained from β-substituted enaminones 2a–j, whereas β-unsubstituted enaminone 4 gave a mixture of cyclic and acyclic products.
Keywords
Enaminones , aza-annulation , Pyridinones , Heterocycles , Fluorinated building blocks
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885080
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