One-pot synthesis of N-heterocycles by tandem carbamoylation–oxidative bromolactamization of ω-alkenylmagnesium bromide

An addition reaction of ω-alkenylmagnesium bromide with p-toluenesulfonyl isocyanate and consecutive oxidative cyclization with iodobenzene diacetate afforded brominated lactams in one-pot. An imine was also applicable to a one-pot synthesis of terminally brominated cyclic amine.