Title of article
TiCl4 mediated preparation of (E)-non-conjugated homoallylic alcohols with α-substituted allylsilanes
Author/Authors
Albury، نويسنده , , Aymara M.M. and Jennings، نويسنده , , Michael P.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
4487
To page
4490
Abstract
The allylation of various aldehydes with α-substituted allylsilanes in the presence of TiCl4 has been investigated. It has been shown that these reagents readily allow for good yields and high to excellent diastereoselectivities (up to >20:1) for a series of aldehydes, thereby providing a means of preparing non-conjugated (E)-homoallylic alcohols in a single step.
Keywords
Allylsilane , natural products , diastereoselective synthesis , allylation , Olefination
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885245
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