Title of article :
First stereoselective synthesis of cytotoxic (−)-kunstleramide
Author/Authors :
Purushotham Reddy، نويسنده , , S. and Venkateswarlu، نويسنده , , Y.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
The first stereoselective synthesis of the cytotoxic (−)-kunstleramide (1) has been reported from simple and commercially available starting material 3,4-dimethoxyphenylpropanol. The key steps involved are the MacMillan α-hydroxylation, Horner–Wadsworth–Emmons (HWE) olefination, and amide-Wittig olefination.
Keywords :
dienamides , Kunstleramide , Cytotoxic , Beilschmiedia kunstleri , MacMillan ?-hydroxylation , Amide-Wittig olefination
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
