Title of article
Diastereoselective synthesis of 2,3-disubstituted 1-arylazetidines via NaBH4-promoted facile reduction of C-3 functionalized azetidin-2-ones
Author/Authors
Mehra، نويسنده , , Vishu and Neetu and Kumar، نويسنده , , Vipan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
4763
To page
4766
Abstract
A facile diastereoselective synthesis of 2,3-disubstituted 1-arylazetidines has been reported via NaBH4-promoted reduction of C-3 functionalized azetidin-2-ones. Since the developed protocol does not involve the use of a Lewis acid, the methodology does not suffer from typical drawbacks of the conventional protocol.
Keywords
?-Lactam synthon , Reduction , sodium borohydride , Azetidin-2-one , Azetidine
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885350
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