Title of article :
Synthesis and antioxidant activity of new C-3 sulfenyl indoles
Author/Authors :
Silveira، نويسنده , , Claudio C. and Mendes، نويسنده , , Samuel R. and Soares، نويسنده , , Josemar R. and Victoria، نويسنده , , Francine N. and Martinez، نويسنده , , Débora M. and Savegnago، نويسنده , , Lucielli، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A convenient and efficient methodology for the synthesis of new C-3 sulfur-substituted indoles under CeCl3·7H2O promotion is reported. Model bis(indol-3-yl)sulfide 4a and bis(indol-3-yl)sulfone 5a proved to display potent antioxidant activity at the low micromolar level, in DPPH, ABTS, and FRAP assays, as well as in the inhibition of the peroxidation of linoleic acid.
Keywords :
antioxidant activity , Microwave-assisted synthesis , Cerium(III) chloride heptahydrate , Indole sulfide derivatives
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
