Author/Authors :
Carlos and Gonzلlez-Calderَn، نويسنده , , Davir and Benيtez-Puebla، نويسنده , , Luis J. and Gonzلlez-Gonzلlez، نويسنده , , Carlos A. and Assad-Hernلndez، نويسنده , , Salomَn and Fuentes-Benيtez، نويسنده , , Aydeé and Cuevas-Yلٌez، نويسنده , , Erick and Corona-Becerril، نويسنده , , David and Gonzلlez-Romero، نويسنده , , Carlos، نويسنده ,
Abstract :
TBDMS alkyl ethers are efficiently cleaved to the corresponding hydroxyl compounds upon heating (conventional or microwave) in methanol solution containing 20 mol % CuSO4·5H2O. Intramolecular chemoselective experiments showed that TBDMS alkyl ethers are selectively cleaved in the presence of TIPS or TBDPS aryl ethers. Competition experiments also showed that TBDMS alkyl ethers were selectively cleaved in the presence of TBDPS alkyl ethers.
Keywords :
alcohols , Silyl ethers , Deprotection , protective groups , Cupric sulfate pentahydrate
