Title of article
Development of one-pot synthesis of α-hydroxy α-trifluoromethyl amides
Author/Authors
Meng، نويسنده , , Zhaoyang and Butcher، نويسنده , , William E.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
5133
To page
5136
Abstract
An efficient one-pot-three-step method has been developed to assemble readily available aryl or heteroaryl halides, methyl trifluoropyruvate, and amines into biologically important α-hydroxy α-trifluoromethyl amides without isolation of any intermediates.
Keywords
Bodroux reaction , Halogen–magnesium exchange reaction , ?-Hydroxy ?-trifluoromethyl amides , One-pot
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885515
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