Title of article :
T3P®-promoted Kabachnik–Fields reaction: an efficient synthesis of α-aminophosphonates
Author/Authors :
Milen، نويسنده , , Mلtyلs and ءbrلnyi-Balogh، نويسنده , , Péter and Dancsَ، نويسنده , , Andrلs and Frigyes، نويسنده , , Dلvid and Pongَ، نويسنده , , Lلszlَ and Keglevich، نويسنده , , Gyِrgy، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A simple and efficient synthesis of α-aminophosphonates has been developed via the one-pot three-component reactions of aldehydes, amines, and trialkyl phosphites. The reactions occurred rapidly at room temperature in the presence of 1 equiv of propylphosphonic anhydride (T3P®) as the condensing agent, and the α-aminophosphonate products were obtained in high yields.
Keywords :
Kabachnik–Fields reaction , Three-component condensation , T3P® , Mechanism , ?-Aminophosphonates
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
