Title of article :
A solvent-free amidation of vinylogous esters via direct aziridination
Author/Authors :
McLaughlin، نويسنده , , Emily C. and Shrestha، نويسنده , , Anuska and Fletcher، نويسنده , , Madison H. and Steinauer، نويسنده , , Nathaniel S. and Shinn، نويسنده , , Min Kyung and Shahid، نويسنده , , Sabrina M.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A microwave-mediated aziridination of α,β-unsaturated ketones and esters through the decomposition of ethyl azidoformate has been developed. When the same atom-economical reaction conditions are applied to cyclic vinylogous esters, N-functionalization at the α-position occurs. Based on NMR analysis, these amidation products appear to be formed from the desired aziridine in moderate to good yields.
Keywords :
Amidation , Microwave-mediated synthesis , Ethyl azidoformate , Vinylogous ester , Aziridination
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
