Title of article :
A highly stereocontrolled asymmetric total synthesis of epimer of (+)-7-deoxypancratistatin
Author/Authors :
Chavan، نويسنده , , Subhash P. and Garai، نويسنده , , Sumanta and Dey، نويسنده , , Chandan and Gonnade، نويسنده , , Rajesh G.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A highly stereocontrolled asymmetric total synthesis of epimer of (+)-7-deoxypancratistatin has been achieved from readily available starting materials via unified strategy employing Sharpless asymmetric dihydroxylation, ring closing metathesis, Overman rearrangement, hydrogenolysis and Bischler–Napieralski reaction in 15 purification steps with 15% overall yield.
Keywords :
7-Deoxypancratistatin , Epimer , sharpless asymmetric dihydroxylation , deoxygenation , Amaryllidaceous alkaloids
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
