Author/Authors :
Habibi-Khorassani ، Sayyed Mostafa نويسنده , , Maghsoodlou، Malek Taher نويسنده , , Shahraki، Mehdi Hashemi نويسنده Power & Water University (Shahid Abbaspour) , , Hashemi Shahri، Marjan نويسنده Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674, Zahedan, Iran , , Aboonajmi، Jasem نويسنده Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674, Zahedan, Iran , , Zarei، Tahere نويسنده Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674, Zahedan, Iran ,
Abstract :
Acetic acid has been applied as an efficient catalyst and a green solvent for the two–component condensation reaction consisting of benzaldehyde, 2-amino-benzamide. The advantages of this protocol was excellent yield, short reaction time, mild reaction conditions, higher availability, low costs, more environmentally friendly, lack of need for column chromatography and simple work-up procedure. In addition, based on the spectral data, the partial order with respect to each reactant was one. Furthermore, useful information regarding the mechanism of the reaction was obtained from studies of the effect of solvent, concentration and catalyst on the rate of the reaction. The results showed that the first step of the mechanism was a rate-determining step. In the studied temperature range, the second order rate constant (lnk1, lnk1/T) depended on reciprocal temperature was in good agreement with the Arrhenius and Eyring equations. These data provided the suitable plots for calculating the activation energy (Ea = 52.80 kJmol-1) and the related kinetic parameters (?G‡ = 63.74 kJmol-1, ?S‡ = -54.22 Jmol-1 and ?H‡ = 50.28 kJ mol-1) of the reaction.
